[article]
| Titre : |
Coprescription of antipsychotics and benzodiazepines at hospital discharge |
| Titre original : |
Coprescription d’antipsychotiques et benzodiazépines en sortie d’hospitalisation |
| Type de document : |
texte imprimé |
| Auteurs : |
Maxime Demourgues (1996-), Auteur ; Alexandre Richaud, Auteur ; Julie Thiec, Auteur |
| Année de publication : |
2026 |
| Article en page(s) : |
pp.369-376 |
| Note générale : |
Autres auteurs : Anne-Laure Debruyne, Sacha Guillemin, Marie Tournier, Francesco Salvo, Emmanuelle Queuille. |
| Langues : |
Anglais (eng) |
| Mots-clés : |
antipsychotiques benzodiazépines anxiolytiques associations médicamenteuses pharmacoépidémiologie |
| Résumé : |
Introduction
Antipsychotics and benzodiazepines (BZD) are known to increase the risk of sedation, dizziness, cognitive impairment and even confusion when used in combination because of their psycholeptic properties. Antipsychotics and BZD coprescription should therefore be minor at discharge from a psychiatric hospital, especially for conventional sedative antipsychotics (CS-AP), such as cyamemazine, levomepromazine, or loxapine which are often used as adjunctive treatments like BZD.
Objectives
The primary objective was to investigate the prevalence of prescription of CS-AP, long-term antipsychotics (LT-AP), and BZD among patients discharged from hospitalization in psychiatry. The secondary objective was to assess factors associated with CS-AP and BZD coprescription.
Material and methods
A retrospective study was conducted by collecting all discharge prescriptions from patients discharged from a psychiatric hospital in 2022 and 2023. To assess prevalence, antipsychotic and BZD use was registered when at least one medication from these classes was prescribed at discharge. Multivariate logistic regression analysis was used to assess factors associated with CS-AP and BZD coprescription. Sensitivity analyses were performed to corroborate our results. |
| Permalink : |
https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124165 |
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.369-376
[article]
|  |