[article]
| Titre : |
Intravenous ketamine for suicide ideation in borderline personality and depression [Kétamine intraveineuse pour les idées suicidaires dans le trouble borderline et la dépression] |
| Auteurs : |
BACHIR Yara, Auteur ; KASSAB Raymond, Auteur ; HALLAL Caroline, Auteur ; CHARBEL CORDAHI Colin, Auteur ; BOU KHALIL Rami, Auteur ; EL-HACHEM Charline, Auteur |
| Année de publication : |
2026 |
| Article en page(s) : |
104-107 |
| Note générale : |
Fig./22 réf.bibl. |
| Langues : |
Anglais (eng) |
| Mots-clés : |
KETAMINE COMORBIDITE CAS CLINIQUE ETAT LIMITE TROUBLE DE L'HUMEUR DEPRESSION RESISTANTE IDEATION SUICIDAIRE |
| Résumé : |
Objective : This case report explores the efficacy of intravenous Ketamine in treating active suicidal ideation in a 24-year-old female with comorbid major depressive disorder (MDD), borderline personality disorder (BPD), posttraumatic stress disorder (PTSD), and functional neurological disorder (FND). Case description : The patient, with a history of multiple suicide attempts and treatment-resistant MDD, demonstrated significant improvement following nine intravenous ketamine sessions. The Montgomery-Åsberg Depression Rating Scale score decreased from 45 to 11, accompanied by sustained reductions in impulsivity, irritability, and depressive symptoms. Discussion : This report highlights ketamine's rapid action on glutamate pathways and its potential benefits in complex psychiatric profiles where traditional treatments like electroconvulsive therapy often fail. A proposed staging model for suicidal behavior management underscores the importance of early intervention with non-classical treatments in high-risk cases. Conclusion : Intravenous ketamine offers a promising therapeutic option for patients with severe suicidality and comorbidities, warranting further research on its long-term efficacy and safety. [résumé d'auteur] |
| En ligne : |
https://doi.org/10.1016/j.encep.2025.04.008 |
| Permalink : |
https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124015 |
in L'encéphale > n°1 (Février 2026 Vol. 52) . - 104-107
[article]
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