Auteur BOU KHALIL Rami
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Documents disponibles écrits par cet auteur (4)
Ajouter le résultat dans votre panier Faire une suggestion Affiner la recherche Interroger des sources externesIntravenous ketamine for suicide ideation in borderline personality and depression [Kétamine intraveineuse pour les idées suicidaires dans le trouble borderline et la dépression] / BACHIR Yara in L'encéphale, n°1 (Février 2026 Vol. 52)
Titre : Intravenous ketamine for suicide ideation in borderline personality and depression [Kétamine intraveineuse pour les idées suicidaires dans le trouble borderline et la dépression] Auteurs : BACHIR Yara, Auteur ; KASSAB Raymond, Auteur ; HALLAL Caroline, Auteur ; CHARBEL CORDAHI Colin, Auteur ; BOU KHALIL Rami, Auteur ; EL-HACHEM Charline, Auteur Année de publication : 2026 Article en page(s) : 104-107 Note générale : Fig./22 réf.bibl. Langues : Anglais (eng) Mots-clés : KETAMINE COMORBIDITE CAS CLINIQUE ETAT LIMITE TROUBLE DE L'HUMEUR DEPRESSION RESISTANTE IDEATION SUICIDAIRE Résumé : Objective : This case report explores the efficacy of intravenous Ketamine in treating active suicidal ideation in a 24-year-old female with comorbid major depressive disorder (MDD), borderline personality disorder (BPD), posttraumatic stress disorder (PTSD), and functional neurological disorder (FND). Case description : The patient, with a history of multiple suicide attempts and treatment-resistant MDD, demonstrated significant improvement following nine intravenous ketamine sessions. The Montgomery-Åsberg Depression Rating Scale score decreased from 45 to 11, accompanied by sustained reductions in impulsivity, irritability, and depressive symptoms. Discussion : This report highlights ketamine's rapid action on glutamate pathways and its potential benefits in complex psychiatric profiles where traditional treatments like electroconvulsive therapy often fail. A proposed staging model for suicidal behavior management underscores the importance of early intervention with non-classical treatments in high-risk cases. Conclusion : Intravenous ketamine offers a promising therapeutic option for patients with severe suicidality and comorbidities, warranting further research on its long-term efficacy and safety. [résumé d'auteur] En ligne : https://doi.org/10.1016/j.encep.2025.04.008 Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124015
in L'encéphale > n°1 (Février 2026 Vol. 52) . - 104-107[article]Réservation
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Titre : Cognitive functions of patients treated with chemotherapy : A comparative study [Les fonctions cognitives des sujets sous chimiothérapie : étude comparative] Auteurs : BOU KHALIL Rami, Auteur ; HADDAD Fady, Auteur ; CORDAHI Colin Charbel, Auteur ; FIANI Dimitri, Auteur ; MOUKARZEL Jean-Marie, Auteur ; CHAMOUN Yara, Auteur ; KOURIE Hampig Raphael, Auteur ; RICHA Sami, Auteur ; KATTAN Joseph, Auteur Année de publication : 2024 Article en page(s) : 524-530 Note générale : Fig./Tabl./35 réf. bibliogr. Langues : Anglais (eng) Mots-clés : CHEMOBRAIN LIBAN CANCEROLOGIE CANCER FONCTION COGNITIVE THERAPEUTIQUE MEDICAMENTEUSE Résumé : Objectives : Chemobrain is a well-established clinical syndrome that has become an increasing concern because of the growing number of long-term cancer survivors. It refers to the post-chemotherapy related cognitive dysfunction. The aim of this study was to objectively assess the impact of cancer treatment on the cognition of cancer patients. Methods : This was a convenience sample comparative study conducted at the Hematology and Oncology Department of Hôtel Dieu de France University Hospital in Beirut, Lebanon. It included cancer patients (G1) aged under 65 years who had already been treated for cancer compared to two control groups. The first control group (G2) consisted of treatment-naïve cancer patients aged under 65, and the second group (G3) was recruited from a pool of healthy controls aged between 40 and 65 years. All participants were asked to complete the part B of the trail making test (TMT) and the digital symbolic substitution test (DSST). Results : In the bivariate analysis, patients in G1 had significantly higher scores than patients in G2 (P = 0.017) and G3 (P < 0.001) on the TMT-B. However, patients in G1 only had lower scores on DSST when compared with G3 (P = 0.017). In the logistic regression taking different groups two-by-two as the dependent variable, the only significant difference was found in the comparison between G2 and G3 with higher TMT-B scores more in favor of belonging to G2 (OR = 0.946; P = 0.003). Conclusions : Our results suggest that, after controlling for anxiety and depression symptoms, patients treated with chemotherapy have significantly poorer outcomes on the DSST and TMT-B than treatment-naïve cancer patients and healthy controls. However, when taking confounding factors into account, the difference only persisted between patients undergoing chemotherapy and healthy controls. These findings are in favor of a multifactor cognitive impairment in patients with cancer partially related to chemotherapeutic treatment. [Résumé d'auteur] En ligne : https://www.em-premium.com/article/1689698 Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=121563
in L'encéphale > n°5 (Octobre 2024 Vol.50) . - 524-530[article]Réservation
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Titre : Positive and negative correlates of suicidal ideations and behaviors in the emergency department of a university hospital in Beirut: A cross-sectional comparative study [Corrélats des idéations et des comportements suicidaires aux urgences] Auteurs : MOURAD Marc, Auteur ; KAZOUR François, Auteur ; SLEILATY G, Auteur ; BOU KHALIL Rami, Auteur ; EL HAGE Wissam, Auteur ; RICHA Sami, Auteur ; SABBAGH C, Auteur Année de publication : 2023 Article en page(s) : 248-253 Note générale : 26 réf. bibliogr./Fig./Tabl. Langues : Anglais (eng) Mots-clés : LIBAN URGENCE PSYCHIATRIQUE SUICIDE FACTEUR DE RISQUE PREVALENCE DEPISTAGE Résumé : This study aims to identify the prevalence and correlates of current suicidal ideations and past suicidal behaviors among psychiatric emergencies. A cross-sectional comparative study was conducted using the Ask Suicide Screening Questions (ASQ) as a screening tool that targeted all patients presenting for a psychiatric emergency in a university hospital in Beirut during a four-month period. One hundred and three patients of all age groups have been divided into a group of patients with a positive suicidal screening (n = 67, 65%), and another one with a negative suicidal screening (n = 36, 35%). Suffering from a personality disorder was found to be a positive correlate of suicide screening (OR: 21.6, 95% CI: 2.6–179.0). Female gender (OR: 4.5, 95% CI: 1.6–13.2) and an elevated number of previous hospitalizations were found to be positive correlates of past suicidal attempts. These correlates should be assessed in the emergency room department (ER) to prevent any subsequent suicidal behavior. [résumé d'auteur] En ligne : https://www.em-premium.com/article/1590263 Format de la ressource électronique : https://www.em-premium.com/article/1590263 Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=121150
in L'encéphale > n°3 (Juin 2023 Vol. 49) . - 248-253[article]Réservation
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Titre : Traumatic life events and its impact on fibromyalgia symptoms through serotonin activity on pain perception and personality traits Auteurs : ZARZOUR Myriam, Auteur ; BOU KHALIL Rami, Auteur Année de publication : 2022 Article en page(s) : 725-728 Note générale : 22 réf. bibliogr./Fig. Langues : Anglais (eng) Mots-clés : SYNDROME POST TRAUMATIQUE DOULEUR FIBROMYALGIE SEROTONINE REVUE DE LA LITTERATURE Résumé : Fibromyalgia is a chronic syndrome characterized by widespread muscular pain and tenderness with no evidence of soft tissue inflammation. Early-life stressors and traumatic events have been described to increase the risk of developing a number of psychiatric conditions, and conditions related to chronic pain in later life such as fibromyalgia on the other hand. In this overview of the literature on the topic, we present the impact that traumatic life events can have on fibromyalgia symptoms through serotonin activity on pain perception and personality traits. [Résumé des auteurs] En ligne : https://www.em-premium.com/article/1556076 Format de la ressource électronique : https://www.em-premium.com/article/1556076 Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=120917
in L'encéphale > n°6 (Décembre 2022 Vol. 48) . - 725-728[article]Réservation
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