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Ajouter le résultat dans votre panierGLP-1 receptor agonists: A paradigm shift for psychiatry? / Sébastien Guillaume in L'encéphale, n°4 (Août 2026 Vol. 52)
Titre : GLP-1 receptor agonists: A paradigm shift for psychiatry? Titre original : Les agonistes du récepteur du GLP-1 : un changement de paradigme pour la psychiatrie ? Type de document : texte imprimé Auteurs : Sébastien Guillaume, Auteur ; CHAUVET-GELINIER Jean-Christophe, Auteur ; Paul Brunault, Auteur Année de publication : 2026 Article en page(s) : pp.341-342 Note générale : Éditorial. Langues : Anglais (eng) Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124160
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Titre : General practitioners’ choices when starting treatment for major depression : Update of Dusmenil et al. survey (2012) in view of new mental health devices [Mise à jour de l’enquête Dusmenil et al. (2012) en vue des nouveaux dispositifs de santé mentale] Titre original : Prise en charge de la dépression en médecine générale de ville : les choix des médecins généralistes lors de l’instauration d’un traitement des épisodes dépressif caractérisé Type de document : texte imprimé Auteurs : Sara Arderiu, Auteur ; Sophie Prébois, Auteur ; Maryse Lapeyre-Mestre, Auteur Année de publication : 2026 Article en page(s) : pp.343-352 Langues : Anglais (eng) Mots-clés : survie psychothérapie soin de santé primaire management dépression aiguë Résumé : Introduction and objectives
A 2011 study on general practitioners’ (GP) management of major depressive disorders (MDD) revealed limited treatment options, predominantly pharmacotherapy. Since then, France has implemented mental health initiatives, including “Mon Soutien Psy”, covering up to 12 psychologist sessions by health insurance (8 during our study). The program “Dispositif de Soins Partagés en Psychiatrie” (DSPP) is a specific scheme implemented in the Occitanie region (South of France) with the aim of improving collaboration between psychiatrists and GPs at a local level. The aim of this study was to investigate MDD care management in primary care according to the implementation of these new schemes.
Methods
We reused the 2011 case vignette survey, adding items related to new schemes. The survey was done by means of electronic-questionnaires sent to GPs by the regional Union of Health professionals in three different French administrative areas (Bouches-du-Rhône and Ille-et-Vilaine, with “Mon Soutien Psy”, and Haute-Garonne for the DSPP).
Results
In total, 158 GPs completed the survey – 69.0% from Haute-Garonne – for a total response rate of 3.4%. Compared with the 2011 survey, there was a significant increase in the number of GPs managing patients in collaboration with a specialist (6.3 versus 3.3%; P < 0.05) and assessing the situation before prescribing an antidepressant (44.2 versus 10.7%; P < 0.00001). GPs were mostly from Haute-Garonne (DSPP area). Attitudes towards psychotherapies had improved since 2011, though some misconceptions persisted. Barriers were no longer the reimbursement or the patient's reluctance to undergo psychotherapy but rather the overly long wait to get an appointment. Overall, MDD management in primary care aligned more closely with the guidelines.
Conclusion
Results indicate positive trends: GPs show greater adherence to MDD management guidelines and a willingness to consult specialists while handling cases independently. Nonetheless, further improvements are necessary with larger studies needed for validation. Recent mental health programs likely contributed to these advancements.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124161
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.343-352[article]Réservation
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Titre : Clinical and sociodemographic characteristics of patients with heart failure and schizophrenia or psychotic disorder in France Titre original : Les caractéristiques cliniques et sociodémographiques des patients avec insuffisance cardiaque et trouble du spectre de la schizophrénie en France Type de document : texte imprimé Auteurs : William Dalfin, Auteur ; Aurélie Bannay, Auteur ; Sylvain Baillot, Auteur Année de publication : 2026 Article en page(s) : pp.353-357 Note générale : Autres auteurs : Vincent Laprévote Langues : Anglais (eng) Mots-clés : insuffisance cardiaque schizophrénie trouble psychotique santé mentale France Résumé : Objectives
To assess the clinical and socio-demographic characteristics of patients hospitalized for heart failure (HF) with schizophrenia or psychotic disorder comorbidity.
Method
We conducted an observational study from the national French PMSI database. We included patients hospitalized with a principal diagnosis of HF between 2019 and 2023, with and without a secondary diagnosis of schizophrenia or psychotic disorder. In total, we included 693,398 HF patients, 7368 with and 686,030 without schizophrenia or psychotic disorder.
Results
Men with HF and schizophrenia or psychotic disorder were on average eight years younger (69.9 vs. 77.8 years), and women were four years younger (79.4 vs. 83.6 years) than men and women without this comorbidity. Overall, HF patients with schizophrenia or psychotic disorder were more often women (57.9 vs. 49.9%) and had a higher prevalence of obesity (29.9 vs. 22.6%), chronic obstructive pulmonary disease (19.6 vs. 14.2%), and stroke (12.6 vs. 10%). The length of stay was longer in patients with schizophrenia (11.7 vs. 10.2 days). Men with HF and schizophrenia or psychotic disorder were on average ten years younger than women with this pathology (69.9 vs. 79.4 years) and had a higher prevalence of myocardial infarction (13.7 vs. 8.3%).
Conclusion
Patients with HF and schizophrenia or psychotic disorder are younger than HF patients without this comorbidity. Despite the younger age, patients with schizophrenia or psychotic disorder have a higher burden of comorbidities and a longer length of stay. Patients with schizophrenia or psychotic disorder, especially men, need close follow-up to prevent the early occurrence of HF.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124162
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.353-357[article]Réservation
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Titre : French psychiatrists’ perspectives on proposed medical aid in dying legislation Titre original : Aide médicale à mourir : position des psychiatres français face au projet de loi Type de document : texte imprimé Auteurs : Emilie Olié, Auteur ; Philippe Courtet, Auteur Année de publication : 2026 Article en page(s) : pp.358-362 Langues : Anglais (eng) Mots-clés : psychiatre euthanasie suicide assisté éthique Résumé : Introduction
France is poised to legalize Medical Aid in Dying (MAiD). Such a law may have potential implications for mental healthcare.
Methods
We conducted an anonymous survey of 168 French psychiatrists between June and July 2024 to assess familiarity with the proposed law, willingness to participate in MAiD, and perceived ethical implications.
Results
Eighteen percent of psychiatrists were unaware of the draft law, while only 9% had precise knowledge. Thirty-seven percent expressed a willingness to participate in MAiD for their patients. Concerns emerged around differentiating rational end-of-life requests from suicidal ideation driven by potentially treatable mental disorders such as depression.
Discussion
The absence of psychiatric assessment in the proposed legislation raises ethical and clinical dilemmas, particularly given the high prevalence of underdiagnosed depression in severe medical conditions. Psychiatrists find themselves balancing suicide-prevention mandates with respect for patient autonomy.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124163
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.358-362[article]Réservation
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Titre : Habilitative and rehabilitative educational interventions as protective factors against cognitive decline in adults with Down syndrome: A retrospective study Titre original : Interventions éducatives habilitatives et rééducatives comme facteurs protecteurs contre le déclin cognitif chez les adultes avec trisomie 21 : étude rétrospective Type de document : texte imprimé Auteurs : Marilena Recupero, Auteur ; Tommasa Zagaria, Auteur ; Flaviana Elia, Auteur Année de publication : 2026 Article en page(s) : pp.363-368 Note générale : Autres auteurs : Margherita Grasso, Filippo Caraci, Concetta Barone, Donatella Greco, Raffaele Ferri, Alessandro Serretti, Serafino Buono. Langues : Anglais (eng) Mots-clés : syndrome de Down trisomie 21 démence déficience intellectuelle profil neuropsychologique interventions éducatives d'habilitation/réadaptation Résumé : Background and objectives
Adults with Down syndrome (DS) face a markedly elevated risk of Alzheimer's disease (AD), yet modifiable environmental factors that modulate cognitive decline remain under-explored. We aimed to determine whether formal education and lifelong habilitative/rehabilitative educational interventions (HREI) preserve neuropsychological functioning in DS.
Methods
We retrospectively reviewed records of 50 adults with DS (median = 41 years). Global cognition and seven Test for Severe Impairment (TSI) domains were compared between individuals with dementia ( n = 25) and matched controls without dementia ( n = 25). Participants were further stratified by schooling (0–5 vs. 8–13 years) and HREI exposure/duration.
Results
The dementia group performed significantly worse in praxis, language comprehension, immediate memory, general knowledge, conceptualisation and total TSI score ( P < 0.01). Within this group, ≥ 8 years of schooling and HREI exposure were each associated with higher global cognition and superior performance across up to five domains; no benefit was evident when interventions ceased after age 18. Schooling and HREI did not differentiate participants without dementia.
Conclusion
Formal education and sustained HREI appear to confer cognitive reserve in DS, attenuating AD-related decline. These findings support policies that guarantee educational inclusion and lifelong, structured cognitive-motor enrichment for individuals with DS. Prospective larger-scale studies are warranted to delineate optimal dosage and timing of enrichment programmes in DS.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124164
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.363-368[article]Réservation
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Titre : Coprescription of antipsychotics and benzodiazepines at hospital discharge Titre original : Coprescription d’antipsychotiques et benzodiazépines en sortie d’hospitalisation Type de document : texte imprimé Auteurs : Maxime Demourgues (1996-), Auteur ; Alexandre Richaud, Auteur ; Julie Thiec, Auteur Année de publication : 2026 Article en page(s) : pp.369-376 Note générale : Autres auteurs : Anne-Laure Debruyne, Sacha Guillemin, Marie Tournier, Francesco Salvo, Emmanuelle Queuille. Langues : Anglais (eng) Mots-clés : antipsychotiques benzodiazépines anxiolytiques associations médicamenteuses pharmacoépidémiologie Résumé : Introduction
Antipsychotics and benzodiazepines (BZD) are known to increase the risk of sedation, dizziness, cognitive impairment and even confusion when used in combination because of their psycholeptic properties. Antipsychotics and BZD coprescription should therefore be minor at discharge from a psychiatric hospital, especially for conventional sedative antipsychotics (CS-AP), such as cyamemazine, levomepromazine, or loxapine which are often used as adjunctive treatments like BZD.
Objectives
The primary objective was to investigate the prevalence of prescription of CS-AP, long-term antipsychotics (LT-AP), and BZD among patients discharged from hospitalization in psychiatry. The secondary objective was to assess factors associated with CS-AP and BZD coprescription.
Material and methods
A retrospective study was conducted by collecting all discharge prescriptions from patients discharged from a psychiatric hospital in 2022 and 2023. To assess prevalence, antipsychotic and BZD use was registered when at least one medication from these classes was prescribed at discharge. Multivariate logistic regression analysis was used to assess factors associated with CS-AP and BZD coprescription. Sensitivity analyses were performed to corroborate our results.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124165
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.369-376[article]Réservation
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Titre : Factor structure and psychometric properties of the French Versions of the Big Five Inventory-2 Short (BFI-2-S) and Extra-Short (BFI-2-XS) informant-report forms Titre original : Structure factorielle et qualités psychométriques des versions françaises des formes courte (BFI-2-S) et extra-courte (BFI-2-XS) du Big Five Inventory-2 Type de document : texte imprimé Auteurs : Baptiste Lignier, Auteur ; Jean-Michel Petot, Auteur ; Pierre De Oliveira, Auteur Année de publication : 2026 Article en page(s) : pp.377-385 Note générale : Autres auteurs : Michel Nicolas, Brice Canada, Robert Courtois, Oliver P. John, Odile Plaisant, Christopher J. Soto. Langues : Anglais (eng) Mots-clés : Cinq grands facteurs de la personnalité facettes de la personnalité invariance de mesure fiabilité modélisation par équations structurelles Résumé : Objectives
A growing body of research has recently highlighted that informant-report is a unique and too often neglected source of personality information. Several personality questionnaires have a form that can be filled out by informants, including the second version of the Big Five inventory (BFI-2), which uses 60 items to assess five major personality dimensions or domains and 15 facets. However, researchers sometimes need shorter questionnaires. The objective of this study was to verify the psychometric properties of the two short forms of the BFI-2 informant-report.
Methods
We asked 1445 students of psychology and sports science and technology to describe a person they know well, and we obtained the complete description of 1380 people. We used exploratory structural equation models to analyze the factor structure of the two sets of items making up the 30-item BFI-2-S, which provides the assessment of the “Big Five” domains and 15 facets (6 items per domain, 2 items per facet), and the 15-item BFI-2-XS which only provides the assessment of the Big Five. We assessed the psychometric properties of the scales measuring the big five domains using conventional indices, and the psychometric properties of the BFI-2-S facets based on the significance and magnitude of the observed and residual correlations between the two items of which they are composed.
Results
The analyses showed excellent fits to the data of the five-factor models. For both questionnaires, almost all items had a high loading on the expected factor, and the cross-loadings overall were small. The correlations between the factors were also small, which indicated discriminant validity. The correlations of the short form scales with the full BFI-2 scales were very large, including the facet scales of the BFI-2-S, indicating excellent concurrent validity. Multigroup analyses suggested differential functioning of certain items, but the magnitude of this bias was small to negligible and insufficient to explain differences according to the gender and age of the people described.
Discussion
The two short forms of the informant-report BFI-2 presented the expected factorial structure and had satisfactory psychometric properties. When the informants were students, they provided reliable and valid descriptions of older people, engaged in family, professional and social life and who often were not available to participate in personality studies. However, it is unknown whether this conclusion can generalize to less educated informants.
Conclusion
The 30-item BFI-2-S and the 15-item BFI-2-XS informant-report forms provide a valid substitute for the full BFI-2 when external circumstances limit the time available for data collection, provided that it is possible to call on reliable informants.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124166
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.377-385[article]Réservation
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Titre : Mental health in physiotherapy students: A nationwide study Titre original : Santé mentale chez les étudiants en kinésithérapie : une étude nationale Type de document : texte imprimé Auteurs : Mathilde Jacquot, Auteur ; Tanguy Lallement, Auteur ; Romain Colle, Auteur Année de publication : 2026 Article en page(s) : pp.386-393 Note générale : Autres auteurs : Fabrice Jollant, Emmanuelle Corruble, Ariel Frajerman. Langues : Anglais (eng) Mots-clés : dépression étudiants en kinésithérapie troubles anxieux idées suicidaires troubles du comportement alimentaire Résumé : Introduction
The prevalence of psychiatric disorders in young adults increased with the COVID-19 pandemic. The prevalence of mental disorders among physiotherapy students increased. Our study aimed to present the results on the mental health status of physiotherapy students in France since the COVID-19 pandemic.
Methods
An online cross-sectional survey was performed between October 1st 2023 and November 5th 2023. Anonymous questionnaires were sent to physiotherapy students via academic emails by all physiotherapy schools in France. We assessed the prevalence of depressive symptoms, generalised anxiety symptoms, burnout, eating disorder symptoms, 12-month major depressive disorder and 12-month suicidal ideation, humiliation, sexual harassment, and sexual assaults. Multivariate logistic regression was performed to identify factors associated with major depressive disorder and suicidal ideation.
Results
Among the 12,568 physiotherapy students, 1280 responded (response rate: 10.2%) and were included. The prevalences of depressive symptoms, anxiety symptoms, eating disorder symptoms, 12-month major depressive disorder, and 12-month suicidal ideation were 25%, 23%, 21%, 11% and 11%, respectively. Humiliation, sexual harassment and sexual aggression were reported by 19%, 1.8% and 0.7%, respectively. In multivariable analyses, curriculum year and sexual violence were associated with higher rates of major depressive episodes and suicidal ideation.
Conclusion
This survey is the first to be carried out on French physiotherapy students at a distance from the peak of the COVID-19 pandemic. It revealed a high prevalence of various mental issues. The results of this survey highlighted the urgent need for action to improve the mental health of physiotherapy students in France.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124167
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.386-393[article]Réservation
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Titre : Experience of the diagnostic journey for ADHD in adulthood: A quantitative and qualitative study Titre original : Expérience du parcours diagnostique du TDAH à l’âge adulte : une étude quantitative et qualitative Type de document : texte imprimé Auteurs : Ophélie Verwaerde, Auteur ; Cédric Galéra, Auteur ; Manuel Bouvard, Auteur Année de publication : 2026 Article en page(s) : pp.394-399 Note générale : Autre auteur : Kellen Briot. Langues : Anglais (eng) Mots-clés : TDAH Adulte Diagnostic Parcours Vécu Résumé : Introduction
Attention deficit disorder with or without hyperactivity (ADHD) affects between 2% and 3% of the world's adult population. In France, there is a noticeable lack of understanding of adult ADHD, which is still too often considered a childhood disorder and is sometimes the cause of a delayed diagnosis for these patients.
Method
To assess the diagnostic experience of people diagnosed with ADHD during adulthood, we carried out a quantitative study with a self-questionnaire proposed to 201 patients aged 17 or over, as well as a qualitative study with 8 patient interviews.
Results
In our sample of respondents, 47% felt that they had had a difficult to very difficult diagnostic journey. Throughout the diagnostic process, patients diagnosed with ADHD in adulthood were confronted with various factors influencing their experience, some of which cannot be modified (age, gender, personal experiences, characteristics of the disorder, etc.), and some of which may have had an impact on the direction this process took. For the rest, the patient's surroundings and the encountered care providers played a major role in the patient's experience of the people around him/her and their beliefs, the patient him/herself, or the physicians met, and their responses and attitudes towards the patient. These factors were all evaluated in this study. Interview analysis of these patients’ experiences reflected the serious consequences of misdiagnosis. Even though ADHD has been recognized and defined for many years, the persistence of controversy, beliefs and even misinformation, with disagreements sometimes even within the medical profession, have impacted the patient's journey. However, the diagnosis of ADHD, albeit later in life, is generally well accepted by patients who express relief from the guilt associated with their past experiences. This diagnosis also helps reduce the consumption of medical treatments, because of an adapted care, and represents a key for these patients to understand their own identity.
Conclusion
The diagnostic journey for adult ADHD sufferers is long and difficult. Efforts to raise awareness of adult ADHD, both among medical staff and the general public, as well as the introduction of tools to help facilitate this diagnostic journey still need to be developed.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124168
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.394-399[article]Réservation
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Titre : A naturalistic study on anaesthesia awareness during electroconvulsive therapy Titre original : Une étude naturalistique rétrospective française sur la mémorisation lors des procédures d’électroconvulsivothérapie Type de document : texte imprimé Auteurs : Camille Rouvière, Auteur ; Romain Dumont, Auteur ; Samuel Bulteau, Auteur Année de publication : 2026 Article en page(s) : pp.400-405 Note générale : Autres auteurs : Anne Sauvaget, Andrew Laurin. Langues : Anglais (eng) Mots-clés : Électroconvulsivothérapie curarisation mémorisation rappel anesthésie Résumé : Introduction
Electroconvulsive therapy (ECT) is a major non-pharmacological treatment performed under general anaesthesia for severe and/or treatment-resistant psychiatric disorders. While the effectiveness of ECT has been well-demonstrated, the safety of the procedure remains a key clinical concern. Among the possible complications of general anaesthesia, anaesthesia awareness with recall (AAWR) is feared and can lead to serious psychological consequences. There is very little data on AAWR during ECT procedures. In this context, the main objective of our study was to assess the rate of AAWR during ECT procedures.
Method
We conducted a retrospective observational study of the medical records for patients treated with ECT between 2020 and 2024 at the Nantes University Hospital Centre, France.
Results
Of the 4994 ECT sessions analysed, six AAWR events (1.2‰) were recorded. AAWR occurred during the consolidation phase in four patients, characterized by a feeling of paralysis during induction or awakening, and resulted in the discontinuation of ECT for two patients. Considering these findings, we propose an algorithm for detecting and managing AAWR during ECT treatment.
Conclusion
ECT does not appear to present an increased risk of AAWR. Nonetheless it is important to systematically check for AAWR, make a report in the medical record, and provide effective therapies that exist for psychological trauma.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124169
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.400-405[article]Réservation
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Titre : Use of service and treatment adequacy in health students with depression Titre original : Recours aux soins et adéquation de la prise en charge chez les étudiants en santé souffrant de dépression Type de document : texte imprimé Auteurs : Ariel Frajerman, Auteur ; Boris Chaumette, Auteur ; Marie-Odile Krebs, Auteur Année de publication : 2026 Article en page(s) : pp.406-414 Note générale : Autre auteur : Yannick Morvan. Langues : Anglais (eng) Mots-clés : consommation soins épisode dépressif caractérisé étudiants en médecine étudiants dentaire étudiants en pharmacie Résumé : Introduction
Our study aimed to measure the prevalence of service use and adequate treatment in health students and to compare medical, dental and pharmacy specialties.
Methods
In 2021, we conducted a survey at Université Paris Cité for dental and pharmacy students. Data for medical students came from a national study conducted during the same period, using the same procedure. We used the Composite International Diagnostic Interview Short-Form (CIDI-SF) questionnaire to evaluate the presence of Major Depressive Disorder (MDD) in the last year. We asked the subjects if they had consulted health professionals or used pharmacotherapy for psychological problems in the previous year.
Results
Our sample comprised 1595 students, with very few dental students ( N = 76), few pharmacy students ( N = 187) and a vast majority of medical students. Among all students, 30% suffered from MDD, 31% used any pharmacological treatment, 16% anxiolytics, 9.5% hypnotics and 9% antidepressants. Among students with MDD, 33% received adequate treatment, including 30% recommended psychotherapy and 20% recommended pharmacological treatments. Pharmacy and preclinical students (medical students in year 2 or 3) consulted less often a psychiatrist and received less adequate treatment, recommended psychotherapy and recommended pharmacological treatments than the other students.
Discussion
In our study, we found a high prevalence of psychotropic use among health students but only 33% of students with MDD received adequate treatment.
Conclusion
This underlines the need for better detection of psychiatric disorders in health students and improved treatment for them. Specific attention is needed for pharmacy students.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124170
in L'encéphale > n°4 (Août 2026 Vol. 52) . - pp.406-414[article]Réservation
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Titre : Effectiveness of hypnosis in adults with posttraumatic stress disorder (PTSD) Titre original : Efficacité de l’hypnose chez les adultes souffrant d’un trouble de stress post-traumatique (TSPT) : une revue systématique Type de document : texte imprimé Auteurs : Juliette Thellier-Francois, Auteur ; Delphine Binda (1974-), Auteur ; Magali Nicolier (1979-), Auteur Année de publication : 2026 Article en page(s) : pp.415-422 Note générale : Autres auteurs : Emmanuel Haffen, Marie-Céline Maillot,Jean-Baptiste Pretalli, Elisabeth Martin, Djamila Bennabi. Langues : Anglais (eng) Mots-clés : trouble de stress post-traumatique hypnose traitement Résumé : Introduction and objectives
Posttraumatic stress disorder is a common diagnosis in the French population. Current treatments are based on first-line trauma psychotherapies (CBT, exposure therapy, EMDR, and narrative therapy), accompanied by medication, particularly antidepressants. The role of hypnosis in the treatment of posttraumatic stress has been little studied and not yet defined in the literature, despite partially common dissociative processes between hypnosis and posttraumatic stress symptoms.
Method
In our PRISMA systematic review, randomized or uncontrolled clinical trials were included from five databases (PubMed, Web of Science, Google Scholar, PsycInfo, PubPsy).
Results
The 12 articles selected are heterogeneous in terms of population characteristics and study design. The excessive heterogeneity of the studies required the following individual description of the results and hypnosis protocols for each study.
Discussion
A majority of the articles reported complete or partial effectiveness of hypnosis on posttraumatic symptoms and their progression, as well as an improvement in associated depressive and anxiety symptoms. The heterogeneity of methods raised questions about the criteria for assessing psychological trauma and its impact, hypnosis protocols, and the place of hypnosis among internationally recognized trauma therapies.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124171
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Titre : Management of trauma-related nightmares in PTSD: Can doxazosin serve as a pragmatic alternative to prazosin? Titre original : Traitement des cauchemars traumatiques dans le TSPT : la doxazosine, alternative à la prazosine ? Type de document : texte imprimé Auteurs : Gilles Sipahimalani (1996-), Auteur ; Jean-Baptiste Roseau (1980-), Auteur ; Dorone Feingold, Auteur Année de publication : 2026 Article en page(s) : pp.423-432 Note générale : Autres auteurs : Marion Remadi, Chloé Lhermitte, Sonia Houssany-Pissot, Dorothée Defontaine, Frédérique Gignoux-Froment, Sophie Annette, Emeric Saguin. Langues : Anglais (eng) Mots-clés : trouble de stress post-traumatique cauchemars traumatiques alpha-bloquants doxazosine prazosine Résumé : Objectives
Trauma-related nightmares (TRNs), core features of post-traumatic stress disorder (PTSD), partially or fully replicate the traumatic event and are often associated with nocturnal awakenings and significant emotional distress. In light of the imminent withdrawal of prazosin in France, this review explores the potential of doxazosin as a pharmacological alternative while emphasizing the central role of psychotherapeutic interventions in TRNs management.
Methods
Following a brief overview of TRNs and existing therapeutic strategies, both pharmacological and non-pharmacological, this review examines the available evidence on doxazosin, a selective α 1 -adrenergic receptor antagonist, and proposes a practical initiation protocol for clinicians.
Results
Although limited and heterogeneous, the literature suggests that doxazosin may reduce the frequency and intensity of TRNs and improve sleep continuity, particularly in patients with marked adrenergic hyperactivation or those who previously responded to prazosin. Tolerance is generally good and extended-release formulations enable convenient nocturnal dosing. However, randomized controlled trials have produced mixed results due to small sample sizes, population heterogeneity, and comorbidities such as alcohol-related disorders. Across studies, psychotherapeutic interventions remain the most evidence-based and durable treatment for TRNs, and pharmacological options are best considered as adjuncts within an integrated care pathway.
Conclusions
Doxazosin may represent a pragmatic pharmacological option for managing TRNs in PTSD, especially in the context of prazosin withdrawal. Its use should complement, rather than replace, first-line psychotherapeutic approaches and be integrated into a comprehensive, coordinated, and individualized treatment plan with careful monitoring of adverse effects. Larger, well-designed randomized controlled trials are needed to determine optimal dosing, treatment duration, and predictors of response.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124172
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Titre : Causes organiques d’un premier épisode psychotique : revue de la littérature Type de document : texte imprimé Auteurs : Charles Tesnières (1993-), Auteur ; Sophie Meunier, Auteur ; Sonia Dollfus, Auteur Année de publication : 2026 Article en page(s) : pp.433-443 Langues : Français (fre) Mots-clés : premier épisode psychotique diagnostic différentiel psychose secondaire psychose organique Résumé : Introduction
Le premier épisode psychotique (PEP) peut être une modalité de début d’une affection psychiatrique, mais aussi être révélateur d’une pathologie organique. En effet, la littérature rapporte une origine organique dans 5,6 % des PEP. Toutefois, il n’existe aucun consensus international ou national conduisant à une forte disparité des pratiques et à de nombreuses erreurs diagnostiques.
Objectif
Cet article rend compte d’un travail de synthèse portant sur l’identification de troubles organiques pouvant provoquer un premier épisode de psychose chez les patients âgés de 15 à 30 ans.
Méthode
La conduite d’une revue systématique de la littérature associée à une revue sélective spécifique de chaque cause organique a permis d’inclure 569 articles.
Résultats
Quatre-vingt-dix étiologies ou groupes d’étiologies sont identifiées et regroupent des causes neurologiques, auto-immunes, génétiques, endocriniennes, gynécologiques, gastro-entérologiques, inflammatoires et/ou infectieuses. Cette revue identifie des recommandations d’auteurs et des indicateurs pour certaines pathologies.
Conclusion
La réalisation d’un bilan paraclinique systématique pour tout PEP chez un patient âgé de 15 à 30 ans, associée à la prescription d’examens paracliniques supplémentaires en présence d’indicateurs spécifiques, est préconisée afin d’éliminer l’ensemble des causes organiques.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124173
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Titre : Soins sans consentement : du concept de dangerosité à une évaluation du risque Type de document : texte imprimé Auteurs : Pierre Oswald, Auteur ; Thierry Pham, Auteur Année de publication : 2026 Article en page(s) : pp.444-448 Langues : Français (fre) Mots-clés : dangerosité psychiatrique risque soins sous contrainte interdisciplinarité Résumé : Objectif
Explorer les limites des évaluations de la dangerosité psychiatrique en Belgique, France, Royaume-Uni et aux Pays-Bas, et examiner si une évaluation systématique et structurée du risque, soutenue par des compétences médico-légales et une interdisciplinarité renforcées, pouvaient améliorer les décisions de soins sans consentement.
Méthodes
Analyse comparative des cadres législatifs (loi belge du 26 juin 1990, modifiée en 2024 ; Code de la santé publique français ; Mental Health Act 1983 ; Wet verplichte geestelijke gezondheidszorg 2020) et des pratiques d’évaluation, basée sur la littérature et des données statistiques.
Résultats
Les mesures de contrainte augmentent fortement en Belgique, en France, au Royaume-Uni et aux Pays-Bas depuis plus de 10 ans. Les évaluations subjectives de la dangerosité, basées sur des critères légaux flous non révisés, présentent une variabilité importante en Belgique et en France, où les échelles de risque sont absentes, contrairement au Royaume-Uni et aux Pays-Bas, qui développent des initiatives autour de l’évaluation du risque, notamment avec le HCR-20 V3 pour structurer les décisions. Ces échelles offrent une précision validée, mais leur implémentation nécessitera une formation.
Conclusions
Une implémentation d’échelles de risque, combinée à une formation interdisciplinaire et médico-légale inspirée de la ligne Nixon, pourrait réduire les biais subjectifs, la stigmatisation et les traumas, sous réserve d’études confirmant leur efficacité.Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124174
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Titre : Prisons de haute sécurité : jusqu’où peut-on soigner en milieu carcéral ? Type de document : texte imprimé Auteurs : Thomas Fovet, Auteur ; Marion Eck, Auteur ; Béatrice Carton, Auteur Année de publication : 2026 Article en page(s) : pp.449-451 Langues : Français (fre) Mots-clés : prison de haute sécurité principe d'équivalence isolement santé éthique Résumé : En mars 2025, le ministre de la Justice a annoncé que les centres pénitentiaires de Vendin-le-Vieil et Condé-sur-Sarthe accueilleraient dès la fin du mois de juillet 2025 « les 200 plus gros narcotrafiquants du pays » au sein de « Quartiers de lutte contre la criminalité organisée ». Les conditions d’incarcération au sein de ces prisons de haute sécurité seront « très strictes » et auront pour objectif de « couper les personnes détenues du monde extérieur ». Les conséquences négatives de l’isolement carcéral sur la santé des personnes détenues sont richement documentées et de nombreux textes et traités internationaux stipulent que cette mesure ne doit être utilisée que dans des circonstances exceptionnelles, en dernier ressort et pour une durée la plus courte possible au sein des établissements pénitentiaires. Dans cet article, nous interrogeons le rôle des soignants dans ces quartiers de haute sécurité : jusqu’où peut-on appliquer le principe d’équivalence selon lequel les personnes détenues doivent bénéficier de soins équivalents à la population générale ? Nous développons la question de la responsabilité éthique des soignants qui exercent dans des établissements où les conditions d’incarcération sont connues pour leurs effets délétères sur la santé des personnes incarcérées. Permalink : https://ch-poitiers.fr/opac_css/index.php?lvl=notice_display&id=124175
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